Dr. Cristiano SIMONE
University of Bari Aldo Moro, Bari, Italy
Invited by Dr. Souhila MEDJKANE
“Unraveling SMYD3 functions along the Cancer Hallmark trail.”
The seminar will take place in the Institut Jacques Monod seminar room (RB-18B).
Bâtiment Buffon, 15 rue Hélène Brion, Paris 13th.
On Wednesday, September 30th at 11:00 am.
Zoom link for remote attendees:
https://u-paris.zoom.us/j/86114422072?pwd=VzJ0c2pxcHl4OWppekx3MldlM2Y4QT09
Meeting ID: 861 1442 2072
Secret code: 492809
Relevant publications from the speaker
Tailoring a novel colorectal cancer stem cell-targeted therapy by inhibiting the SMYD3/c-MYC axis.
Lepore Signorile et al. 2025, doi: 10.1038/s41392-025-02290-z
The novel SMYD3 inhibitor EM127 impairs DNA repair response to chemotherapy-induced DNA damage and reverses cancer chemoresistance.
Sanese P et al. 2024, doi: 10.1186/s13046-024-03078-9
SMYD3 Modulates AMPK-mTOR Signaling Balance in Cancer Cell Response to DNA Damage.
Lepore Signorile et al. 2023, doi: 10.3390/cells12222644
Welcoming Dr Yoichi Shinkai for 3 months
Pierre-Antoine Defossez extended an invitation to Dr Yoichi Shinkai, leader of the “Cellular Memory Laboratory” at the RIKEN Institute and associate professor at Saitama University, Japan. Thanks to Université Paris Cité and the Labex Who Am I? support, we welcome him...
New pre-print about ZBTB24
Congratulations on the new work "ZBTB24 is a conserved multifaceted transcription factor at genes and centromeres that governs the DNA methylation state and expression of satellite repeats" by Grillo et al. shared on bioRxiv. Read here:...
Congratulations to the Defossez group for their paper published in Nucleic Acid Research
Congratulations to the Defossez team for their paper "A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation" by Yakhou, Azogui, Gupta et al., which was published in Nucleic Acid Research. Read it here: doi:...
Congratulations to the Defossez group for their paper published in Nature Strucural and Molecular Biology
Congratulations to the Defossez group for their paper "A genome-wide screen reveals new regulators of the 2-cell-like cell state" by Gupta, Yakhou et al., published in Nature Structural and Molecular Biology. Read it here: doi: 10.1038/s41594-023-01038-z ...
Ana Bošković seminar – October 4, 2023
Wednesday, October 4th, 2023, at 11:00 am Ana Bošković Epigenetics and Neurobiology unit, EMBL, RomeInvited by Juliette Dabin and Sophie Polo “Mechanisms of embryonic gene regulation” The seminar will take place in the Institut Jacques Monod seminar room (RB-18B)....
Yoichi Shinkai seminar – September 18, 2023
Monday, September 18, 2023, at 10:00 am Yoichi Shinkai RIKEN Saitama, JapanInvited by Pierre-Antoine Defossez “Histone modifications in genome regulation” The seminar will take place in the Buffon auditorium, Institut Jacques Monod. Buffon building, 15 rue Hélène...
Welcome Ariane !
Ariane is our new Postdoc. She will work on the host-parasite interactions project. Welcome in the team Ariane! Read more
Welcome Charles !
Charles is our new ATER (teaching Postdoc). He will work on the SMYD project and, will also be part of the teaching unit for cellular biology and physiology. Welcome in the team Charles! Read more
Dounia Djeghloul seminar – September 6, 2023
Wednesday, September 6, 2023, at 11:00 am Dounia Djeghloul Department of Biochemistry, University of Oxford, Oxford, UKInvited by Claire Rougeulle “Impact of chromatin changes on mitotic chromosome structure and bookmarking” The seminar will take place on Zoom...
Congratulations Marisol and Camille
Congratulations to both Marisol and Camille on passing the doctoral school competition.Welcome to the team ! À lire aussi
YRLS 2023 Congress
Jonathan Weitzman's lab was present at the YRLS 2023 conference held on the Pierre et Marie Curie campus (Sorbonne University) from 11 to 13 June 2023.On this occasion, Aristeidis Panagiotou (PhD) had the opportunity to present a Poster during the day "Today's...
EMBO-XCI meeting in Berlin
Rougeulle lab gathering at the EMBO meeting “X-chromosome inactivation: New insights on its 60th anniversary” held in Berlin 19-22 June 2023. ...
Congratulations to the Defossez team for their paper accepted in NSMB
Congratulations to the Defossez team for their paper "A genome-wide screen reveals new regulators of the 2-cell-like cell state" by Gupta, Yakhou et al., which was accepted in Nature Structural and Molecular Biology. Figure 7, panel E Model for role of novel...
Marie Curie postdoctoral fellowship
June 8th 2023: Congratulations to Juliette Dabin for being awarded a postdoctoral fellowship as part of the Marie Skłodowska-Curie Actions of Horizon Europe to characterize epigenome establishment and maintenance of the inactive X chromosome in response to DNA...
Review on the DNA damage response in chromatin
June 8th 2023: Our review entitled "The DNA damage response in the chromatin context: a coordinated process" is just out in Current Opinion in Cell Biology as part of the Cell Nucleus special issue. À lire aussi
Agathe Subtil seminar – June 7, 2023
Wednesday, June 7th, 2023, at 11:00 am Agathe Subtil CNRS UMR3691, Institut Pasteur, ParisInvited by Slimane Ait-Si-Ali and Sophie Polo “Imprint of Chlamydia infection on the metabolism and epigenome of epithelial host cells” The seminar will take place in the...
Helping the “Palais de la Découverte” for their future exhibition
Katia, research engineer and CRISPR/Cas9 expert, welcomed a team from the "Palais de la Découverte" to help them prepare a future exhibition about genetics in the museum. Discover their visit through this short video (in French): Read more
Maria Rostovskaya seminar – April 26, 2023
Wednesday, April 26th, 2023, at 11:00 am Maria Rostovskaya Babraham Institute, Cambridge, UKInvited by Claire Rougeulle “Molecular timetables of differentiation: making the right shape at the right time” The seminar will take place in the Institut Jacques Monod...
Pierre-Antoine Defossez is nominated to the Editorial Board of “Epigenetics and Chromatin”
April 2023: Pierre-Antoine Defossez is nominated to the Editorial Board of “Epigenetics and Chromatin”. Congratulations! More about the journal's editorial board here:https://epigeneticsandchromatin.biomedcentral.com/about/editorial-board Epigenetics & Chromatin...
Guillaume Lamour seminar – April 19, 2023
Wednesday, April 19th, 2023, at 11:00 am Guillaume Lamour Evry University, FranceInvited by Slimane Ait-Si-Ali “Nanomechanics of stiff and soft biomaterials by atomic force microscopy” The seminar will take place in the Institut Jacques Monod seminar room (RB-18B)....