Jun 11, 2024 | Polo group, Publications
A review from our research group is out for publication in DNA Repair as part of the special issue “Cutting-Edge Perspectives in Genome Maintenance”. This review presents our current knowledge on the contribution of pre-existing and DNA damage-induced...
Jun 5, 2024 | Publications, Rougeulle group
Our latest work carried out by Alfeghaly C. et al. elucidating the mechanism of dampening of X-linked gene expression during pre-implantation development. To discover the role of the long non-coding RNA XIST and its particular partner SPEN click on the link: Nature...
May 6, 2024 | Publications, Rougeulle group
Our latest work by Huret et al. linking X chromosome inactivation to autoimmunity is published in Science Advances This work is discussed in different journals: NewScientist: Autoimmune conditions linked to reactivated X chromosome genes National Geographic: Why women...
Jan 12, 2024 | Polo group, Publications
January 12th 2024: We have uncovered an altered DNA repair activity in H3.3 mutant pediatric high-grade glioma that fosters genome instability independently of previously described oncogenic pathways. Furthermore, we have identified a DNA repair enzyme that sustains...
Sep 8, 2023 | Publications
Congratulations on the new work “ZBTB24 is a conserved multifaceted transcription factor at genes and centromeres that governs the DNA methylation state and expression of satellite repeats” by Grillo et al. shared on bioRxiv. Read here:...
Sep 7, 2023 | Defossez group, Publications
Congratulations to the Defossez team for their paper “A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation” by Yakhou, Azogui, Gupta et al., which was published in Nucleic Acid Research. Read it...
Sep 7, 2023 | Defossez group, Publications
Congratulations to the Defossez group for their paper “A genome-wide screen reveals new regulators of the 2-cell-like cell state” by Gupta, Yakhou et al., published in Nature Structural and Molecular Biology. Read it here: doi:...
Mar 16, 2023 | Defossez group, Publications
Congratulations to Laure and Pierre-Antoine for their collaborative paper accepted in Scientific Reports: “Unchanged PCNA and DNMT1 dynamics during replication in DNA ligase I-deficient cells but abnormal chromatin levels of non-replicative histone H1”...
Feb 3, 2023 | Publications, Rougeulle group
Congratulations to the team members for this new article about “Species-specific regulation of XIST by the JPX/FTX orthologs” published in Nucleic Acids Research (Feb 2023). Graphical abstract In contrast to the mouse, human JPX regulates XIST through...
Dec 15, 2022 | Mezger group, Publications
Aurélie De Thonel and the V Mezger lab released a paper in Nature Communications elucidating the relationship between CBP and HSF2 in a neurodevelopmental disorder, CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder. ...
