Sep 25, 2026 | Ait-Si-Ali group
On September 25, 2026, Silvia successfully defended her thesis: “Epigenetic control of nuclear mechanics and migration via H3K9 methylation at Lamina-Associated Domains in lung cancer cells” Silvia Comunian and the jury members: Yegor Vassetzky, Nicolas Borghi,...
Jun 19, 2026 | Ait-Si-Ali group, Publications
In this paper, we show that SETDB1 regulates the TGFβ-induced secretome and identify EMILIN1, an extracellular matrix protein, as a novel player in this process. EMILIN1 is overexpressed in muscle biopsies from DMD patients and influences both myogenic differentiation...
Sep 15, 2025 | Ait-Si-Ali group, Epigenetics & Cell Fate
Congratulations to Dr. Maeva Zamperoni! On September 15, 2025, Maeva successfully defended her thesis: “Role of the lysine methyltransferase SETDB1 in TGFβ-induced fibrosis in Duchenne Muscular Dystrophy (DMD).” Maeva and the jury members: Pascal Maire, Nicolas...
Jan 8, 2025 | Ait-Si-Ali group
Welcome Caroline to our team! We’re excited to have Caroline joining Dr. Ait-si-Ali’s team! She comes to us as an M2 student from the GENE2 master’s program at Université Paris-Saclay. Working with Dr. Guillaume Velasco, Caroline will study the...
Jan 8, 2025 | Ait-Si-Ali group
Welcome Minh to Slimane Ait-si-ali’s team! We are delighted to welcome Mynh, an M2 student from the GENE2 master’s program at Université Paris-Saclay, to Dr. Ait-si-Ali’s team. Mynh will be investigating the role of SETDB1 in Duchenne muscular...
Dec 21, 2024 | Ait-Si-Ali group, Publications
New review: Genetic diseases of epigenetic machinery The development of sequencing technologies and their increased accessibility in clinical services and genetic laboratories have considerably accelerated the identification of genetic variants associated with rare...
Dec 18, 2024 | Ait-Si-Ali group
Congratulations to Guillaume! Congratulations to Dr Guillaume Velasco on obtaining his Habilitation à Diriger des Recherches (HDR) this Wednesday, December 18th. A well-deserved accomplishment! Jury members: Giséle Bonne, Jean-Charles Cadoret, Fabienne Malagnac and...
Dec 14, 2023 | Ait-Si-Ali group, Symposia and seminars
Slimane Ait-Si-Ali and Guillaume Velasco are joining forces with Frédérique Magdinier (Inserm U1251, Marseille) to organize the Inserm Workshop 278 “Epigenetics in health: a focus on rare diseases”. © Ateliers Inserm – Réalisation : Audrey Peloni...
