Presentation

The “Epigenetics and Cell Fate” unit is a multidisciplinary research centre, founded in 2009, and located on the Grands Moulins campus of Université Paris Cité.

The research within the centre focuses on the importance of epigenetic regulations in the determination of cell fate and differentiation programs in mammals, under normal and pathological conditions.

Unit retreat in 2021

© Fabrice Ferron

The unit brings together six teams with complementary expertise in the molecular mechanisms of epigenetics (DNA methylation, histone variants and modifications, and non-coding RNAs), their involvement in development and differentiation processes, and their contribution to pathological processes.

Research in the unit is facilitated on a daily basis by a set of technical platforms and support services.

The unit is led by Dr. Valérie MEZGER (director) and Dr. Claire ROUGEULLE (deputy director). Together, they have established a managerial structure allowing the sharing of responsibilities and the delegation of tasks to the senior researchers of the unit. The Management Committee, which includes all the team leaders, takes the strategic decisions. The Lab Council, gathering the team leaders and elected members representing the different categories of personnel, discusses the general decisions concerning the functioning of the centre.

Unit’s organisation chart

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Thomas Graf seminar

Thomas Graf seminar

Monday, December 4, 2023, at 10:00 am Thomas Graf CRG, BarcelonaInvited by Pierre-Antoine Defossez “Mechanisms of cell fate conversions” The seminar will take place on Zoom only:https://u-paris.zoom.us/j/86114422072?pwd=VzJ0c2pxcHl4OWppekx3MldlM2Y4QT09 Contact:...

Yoichi Shinkai seminar

Yoichi Shinkai seminar

Wednesday, November 22, 2023, at 11:00 am Yoichi Shinkai RIKEN Saitama, JapanInvited by Pierre-Antoine Defossez “Lysine methyltransferase EHMT1/GLP (Ehmt1) heterozygous KO mice as a Kleefstra syndrome model: challenging the onset mechanism and developing therapeutic...

We celebrated Science in October

We celebrated Science in October

Every October, we celebrate science through the "Fête de la Science", a popular public event that celebrates science, technology and innovation. It is open to all and helps promote the sharing of knowledge. This year, our Centre was involved in two visits. Our...