The “Epigenetics and Cell Fate” unit is a multidisciplinary research centre, founded in 2009, and located on the Grands Moulins campus of Université Paris Cité.

The research within the centre focuses on the importance of epigenetic regulations in the determination of cell fate and differentiation programs in mammals, under normal and pathological conditions.

Unit retreat in 2021

© Fabrice Ferron

The unit brings together seven teams with complementary expertise in the molecular mechanisms of epigenetics (DNA methylation, histone variants and modifications, and non-coding RNAs), their involvement in development and differentiation processes, and their contribution to pathological processes.

Research in the unit is facilitated on a daily basis by a set of technical platforms and support services.

The unit is led by Dr. Valérie MEZGER (director) and Dr. Claire ROUGEULLE (deputy director). Together, they have established a managerial structure allowing the sharing of responsibilities and the delegation of tasks to the senior researchers of the unit. The Management Committee, which includes all the team leaders, takes the strategic decisions. The Lab Council, gathering the team leaders and elected members representing the different categories of personnel, discusses the general decisions concerning the functioning of the centre.

Unit’s organisation chart

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Maria Rostovskaya seminar

Maria Rostovskaya seminar

Wednesday, April 26th, 2023, at 11:00 am Maria Rostovskaya Babraham Institute, Cambridge, UKInvited by Claire Rougeulle “Molecular timetables of differentiation: making the right shape at the right time” The seminar will take place in the Institut Jacques Monod...

Guillaume Lamour seminar

Guillaume Lamour seminar

Wednesday, April 19th, 2023, at 11:00 am Guillaume Lamour Evry University, FranceInvited by Slimane Ait-Si-Ali “Nanomechanics of stiff and soft biomaterials by atomic force microscopy” The seminar will take place in the Institut Jacques Monod seminar room (RB-18B)....