Dec 23, 2024 | Epigenetics & Cell Fate, Publications, Rougeulle group
What if the presence of two X chromosomes confers functional specificities on female cells and contributes to the different susceptibilites of men and women to certain diseases? One of the X chromosomes is randomly silenced in each female cell from the embryonic...
Nov 27, 2024 | Epigenetics & Cell Fate, Rougeulle group
The discovery that long noncoding RNAs (lncRNAs) are the most abundant gene class in the human genome has sparked significant research, particularly on Xist, a key RNA involved in X-chromosome inactivation. Recent studies have expanded our understanding of...
Jun 18, 2024 | Epigenetics & Cell Fate, Rougeulle group
Congratulations to Léo who defended his thesis work on ” Exploring the link between X chromosome inactivation and the development of human extraembryonic tissues ” . © Rougeulle team À lire aussi Congratulations Dr Carrillo Epigenetics & Cell Fate,...
Jun 5, 2024 | Publications, Rougeulle group
Our latest work carried out by Alfeghaly C. et al. elucidating the mechanism of dampening of X-linked gene expression during pre-implantation development. To discover the role of the long non-coding RNA XIST and its particular partner SPEN click on the link: Nature...
May 6, 2024 | Publications, Rougeulle group
Our latest work by Huret et al. linking X chromosome inactivation to autoimmunity is published in Science Advances This work is discussed in different journals: NewScientist: Autoimmune conditions linked to reactivated X chromosome genes National Geographic: Why women...
Dec 11, 2023 | Rougeulle group
Congratulations to Dr. Emmanuel Cazottes, who defended his PhD work on the “Evolution of X chromosome Inactivation and regulatory non-coding RNAs in primates” on December 6, 2023. © Rougeulle Team Read more Workshop on Epigenetics in Health Ait-Si-Ali group,...
Jun 30, 2023 | Rougeulle group
Rougeulle lab gathering at the EMBO meeting “X-chromosome inactivation: New insights on its 60th anniversary” held in Berlin 19-22 June 2023. ...
Feb 3, 2023 | Publications, Rougeulle group
Congratulations to the team members for this new article about “Species-specific regulation of XIST by the JPX/FTX orthologs” published in Nucleic Acids Research (Feb 2023). Graphical abstract In contrast to the mouse, human JPX regulates XIST through...
Jan 16, 2023 | Rougeulle group
Romina Facchinello is joining the lab for her Master’s internship (Magistère Européen de Génétique). Welcome Romina! Read more New article Publications, Rougeulle groupCongratulations to the team members for this new article about "Species-specific regulation of XIST...
Dec 9, 2022 | Rougeulle group
The French Society of Genetics (SFG) 2022 medal, Janine BEISSON prize, was awarded to Claire ROUGEULLE by her Professor of genetics Bernard DUJON (former president of the SFG) in the presence of the current vice-presidents of the SFG Clément Carré and Frédéric Bernard...
Dec 9, 2022 | Rougeulle group
The team took advantage of a few days on Tinos island to present and discuss its results with the research teams of Edith Heard (EMBL) and Joost Gribnau (Erasmus MC). Nice moments of scientific exchanges between the...
