Congratulations to the team members for this new article about “Species-specific regulation of XIST by the JPX/FTX orthologs” published in Nucleic Acids Research (Feb 2023).
![article rougeulle Graphical abstract](http://epigenetics.u-paris.fr/wp-content/uploads/sites/32/2023/02/article-rougeulle-1.jpg)
Graphical abstract
In contrast to the mouse, human JPX regulates XIST through mechanisms that are independent of JPX mature transcript, but which involve JPX transcription.
© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.
Species-specific regulation of XIST by the JPX/FTX orthologs.
Rosspopoff O, Cazottes E, Huret C, Loda A, Collier AJ, Casanova M, Rugg-Gunn PJ, Heard E, Ouimette JF, Rougeulle C. Nucleic Acids Res. 2023 Feb 2:gkad029. doi: 10.1093/nar/gkad029.
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![Congratulations Dr Carrillo](https://epigenetics.u-paris.fr/wp-content/uploads/sites/32/2024/06/CR-Leo-defense-1-1080x675.jpg)
Congratulations Dr Carrillo
Congratulations to Léo who defended his thesis work on " Exploring the link between X chromosome inactivation and the development of human extraembryonic tissues " . © Rougeulle team À lire aussi
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Article: XIST dampens X chromosome activity in a SPEN-dependent manner during early human development
Our latest work carried out by Alfeghaly C. et al. elucidating the mechanism of dampening of X-linked gene expression during pre-implantation development. To discover the role of the long non-coding RNA XIST and its particular partner SPEN click on the link: Nature...
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Article: Altered X-chromosome inactivation predisposes to autoimmunity
Our latest work by Huret et al. linking X chromosome inactivation to autoimmunity is published in Science Advances This work is discussed in different journals: NewScientist: Autoimmune conditions linked to reactivated X chromosome genes National Geographic: Why women...
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Congratulations Dr. Emmanuel Cazottes
Congratulations to Dr. Emmanuel Cazottes, who defended his PhD work on the “Evolution of X chromosome Inactivation and regulatory non-coding RNAs in primates” on December 6, 2023. © Rougeulle Team Read more