Our latest work carried out by Alfeghaly C. et al. elucidating the mechanism of dampening of X-linked gene expression during pre-implantation development.
To discover the role of the long non-coding RNA XIST and its particular partner SPEN click on the link: Nature Structural and molecular biology
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Seminar Laurent CHATRE –September 9, 2026
Dr. Laurent CHATRE ISTCT, UMR6030 CNRS, Université de Caen Normandie Invited by Dr. Dounia DJEGHLOUL "Reframing Epigenetics: Metabolism, Mitochondria, and Redox as Core Regulatory Layers." The seminar will take place in the Institut Jacques Monod seminar room...
Call for new Research Group Leader
The CNRS is launching a call for applications for a Junior Professor Chair (Chaire de Professeur Junior, CPJ) entitled “Epigenetics of Cellular Fate (EpiDeC)”, hosted at our Centre. All details in this document.
Sophie Polo elected EMBO member
Honored to be part of this prestigious scientific community. Sophie Polo in her laboratory © Romain Redler / Art in research for the Fondation Bettencourt Schueller À lire aussi
New research article on the role of SETDB1 in regulating inflammation and fibrosis in Duchenne muscular dystrophy
In this paper, we show that SETDB1 regulates the TGFβ-induced secretome and identify EMILIN1, an extracellular matrix protein, as a novel player in this process. EMILIN1 is overexpressed in muscle biopsies from DMD patients and influences both myogenic differentiation...