Congratulations to the Defossez team for their paper “A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation” by Yakhou, Azogui, Gupta et al., which was published in Nucleic Acid Research.
Read it here: doi: 10.1093/nar/gkad719
Graphical Abstract
Model for the role of BEND3 in the regulation of bivalent genes expression.
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New research article on histone chaperones with central functions in chromatin repair
In this paper, we identify new players in chromatin repair through a novel approach for the proteomic profiling of DNA repair patches in human cells. Thus, we expand the histone chaperone network involved in repair-coupled chromatin restoration and highlight a...
Welcome to Léa
Léa joins the team as a research assistant. After completing a master's degree in virology, she worked in Strasbourg on grapevine viruses, then on characterizing mRNA degradation in plants at the Institute of Plant Molecular Biology (IBMP). In the Polo team, Léa will...
Sophie Polo receives an Impulscience® grant from the Fondation Bettencourt Schueller
Sophie Polo has been awarded an Impulscience® grant to fund a research project on the establishment and maintenance of the inactive X chromosome in response to DNA breaks. This is wonderful news for the lab ! We thank the Fondation Bettencourt Schueller for their...
Welcome to Léa, new engineer in the team!
Léa joins the lab as a research assistant. She holds a Master's degree in Molecular and Cellular Biology from Sorbonne University. She will contribute to investigate DNA methylation maintenance mechanisms in response to UV damage in mammalian cells. Léa Girard À lire...