Tuesday, October 17th, 2023, at 11:00 am

Jacques Côté

CHU de Québec/Université Laval, Canada
Invited by Sophie Polo and Claire Rougeulle

“MYST-family chromatin modifying complexes in genome expression/stability and disease”

The seminar will take place in the Institut Jacques Monod seminar room (RB-18B). Buffon building, 15 rue Hélène Brion, Paris 13th.

Zoom link for remote attendees:

Contact: sophie.polo@univ-paris-diderot.fr


Relevant publications from the speaker:

Recurrent chromosomal translocations in sarcomas create a megacomplex that mislocalizes NuA4/TIP60 to Polycomb target loci.
Sudarshan D, Avvakumov N, Lalonde ME, Alerasool N, Joly-Beauparlant C, Jacquet K, Mameri A, Lambert JP, Rousseau J, Lachance C, Paquet E, Herrmann L, Thonta Setty S, Loehr J, Bernardini MQ, Rouzbahman M, Gingras AC, Coulombe B, Droit A, Taipale M, Doyon Y, Côté J. Genes Dev. 2022 Jun 1;36(11-12):664-683. doi: 10.1101/gad.348982.121.

Antagonistic relationship of NuA4 with the non-homologous end-joining machinery at DNA damage sites.
Ahmad S, Côté V, Cheng X, Bourriquen G, Sapountzi V, Altaf M, Côté J. PLoS Genet. 2021 Sep 20;17(9):e1009816. doi: 10.1371/journal.pgen.1009816.

Phospho-dependent recruitment of the yeast NuA4 acetyltransferase complex by MRX at DNA breaks regulates RPA dynamics during resection.
Cheng X, Jobin-Robitaille O, Billon P, Buisson R, Niu H, Lacoste N, Abshiru N, Côté V, Thibault P, Kron SJ, Sung P, Brandl CJ, Masson JY, Côté J. Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10028-10033. doi: 10.1073/pnas.1806513115.


Read more

Thomas Graf seminar

Thomas Graf seminar

Monday, December 4, 2023, at 10:00 am Thomas Graf CRG, BarcelonaInvited by Pierre-Antoine Defossez “Mechanisms of cell fate conversions” The seminar will take place on Zoom only:https://u-paris.zoom.us/j/86114422072?pwd=VzJ0c2pxcHl4OWppekx3MldlM2Y4QT09 Contact:...

Yoichi Shinkai seminar

Yoichi Shinkai seminar

Wednesday, November 22, 2023, at 11:00 am Yoichi Shinkai RIKEN Saitama, JapanInvited by Pierre-Antoine Defossez “Lysine methyltransferase EHMT1/GLP (Ehmt1) heterozygous KO mice as a Kleefstra syndrome model: challenging the onset mechanism and developing therapeutic...

We celebrated Science in October

We celebrated Science in October

Every October, we celebrate science through the "Fête de la Science", a popular public event that celebrates science, technology and innovation. It is open to all and helps promote the sharing of knowledge. This year, our Centre was involved in two visits. Our...