Dr. Charles Williams
MRC Centre for Regenerative Medicine, The University of Edinburgh
Invited by Dr. Dounia DJEGHLOUL
“Mitotic bookmarking and chromatin regulation: from neural stem cell identity to brain tumour dependency.”
The seminar will take place in the Institut Jacques Monod seminar room (RB-18B).
Bâtiment Buffon, 15 rue Hélène Brion, Paris 13th.
On Wednesday, September 23rd at 11:00 am.
Zoom link for remote attendees:
https://u-paris.zoom.us/j/86114422072?pwd=VzJ0c2pxcHl4OWppekx3MldlM2Y4QT09
Meeting ID: 861 1442 2072
Secret code: 492809
Relevant publications from the speaker
SOX2 phosphorylation during mitosis limits genomic damage.
Williams, C.A.C. et al. Genes & Development 40, 185-198 (2026). DOI: 10.1101/gad.352664.125
Post-translational modification of SOX family proteins: Key biochemical targets in cancer?
Williams, C.A.C., Soufi, A. and Pollard, S.M. Seminars in Cancer Biology (2020). DOI: 10.1016/j.semcancer.2019.09.009
An ERK5-KLF2 signalling module regulates early embryonic gene expression and telomere rejuvenation in stem cells.
Williams, C.A.C. et al. Biochemical Journal (2021). DOI: 10.1042/BCJ20210646
Erk5 Is a Key Regulator of Naive-Primed Transition and Embryonic Stem Cell Identity.
Williams, C.A.C. et al. Cell Reports (2016). DOI: 10.1016/j.celrep.2016.07.033
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