Dr. Charles WILLIAMS

MRC Centre for Regenerative Medicine, The University of Edinburgh

Invité par Dr. Dounia DJEGHLOUL

Mitotic bookmarking and chromatin regulation: from neural stem cell identity to brain tumour dependency.

Le séminaire se tiendra à l’Institut Jacques Monod, salle François Jacob (RB-18B). Bâtiment Buffon,

15 rue Hélène Brion, Paris 13.

Le mercredi 23 septembre 2026 à 11 h.

Lien Zoom pour les participant·e·s à distance :

https://u-paris.zoom.us/j/86114422072?pwd=VzJ0c2pxcHl4OWppekx3MldlM2Y4QT09

ID de réunion : 861 1442 2072

Code secret : 492809

Publications de l’intervenant :

SOX2 phosphorylation during mitosis limits genomic damage.
Williams, C.A.C. et al. Genes & Development 40, 185-198 (2026). DOI: 10.1101/gad.352664.125

Post-translational modification of SOX family proteins: Key biochemical targets in cancer?
Williams, C.A.C., Soufi, A. and Pollard, S.M. Seminars in Cancer Biology (2020). DOI: 10.1016/j.semcancer.2019.09.009

An ERK5-KLF2 signalling module regulates early embryonic gene expression and telomere rejuvenation in stem cells.
Williams, C.A.C. et al. Biochemical Journal (2021). DOI: 10.1042/BCJ20210646

Erk5 Is a Key Regulator of Naive-Primed Transition and Embryonic Stem Cell Identity.
Williams, C.A.C. et al. Cell Reports (2016). DOI: 10.1016/j.celrep.2016.07.033