Dr. Frédéric Frottin

I2BC, Gif-sur-Yvette, France

Invited by Dr. Valérie Mezger

 

The nucleolus as a hot spot in nuclear proteostasis – Molecular basis of the accumulation of misfolded proteins into the nucleolus

 

The seminar will take place in the Institut Jacques Monod seminar room (RB-18B).

Bâtiment Buffon, 15 rue Hélène Brion, Paris 13th.

On Wednesday, April 8that 11:00 am.

 

 

Relevant publications from the speaker:

The nucleolus functions as a phase-separated protein quality control compartment.

Frottin F, Schueder F, Tiwary S, Gupta R, Körner R, Schlichthaerle T, Cox J, Jungmann R, Hartl FU, Hipp MS. Science. 2019 Jul 26;365(6451):342-347.

doi: 10.1126/science.aaw9157.

 

Advances in nuclear proteostasis of metazoans.

Buggiani J, Meinnel T, Giglione C, Frottin F. Biochimie. 2024 Nov;226:148-164.

doi: 10.1016/j.biochi.2024.04.006.

 

Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model.

Frottin F, Pérez-Berlanga M, Hartl FU, Hipp MS. Elife. 2021 Jun 23;10:e62718.

doi: 10.7554/eLife.62718.

Welcome to Léa

Welcome to Léa

Léa joins the team as a research assistant. After completing a master's degree in virology, she worked in Strasbourg on grapevine viruses, then on characterizing mRNA degradation in plants at the Institute of Plant Molecular Biology (IBMP). In the Polo team, Léa will...