Dr. Frédéric Frottin

I2BC, Gif-sur-Yvette, France

Invited by Dr. Valérie Mezger

 

The nucleolus as a hot spot in nuclear proteostasis – Molecular basis of the accumulation of misfolded proteins into the nucleolus

 

The seminar will take place in the Institut Jacques Monod seminar room (RB-18B).

Bâtiment Buffon, 15 rue Hélène Brion, Paris 13th.

On Wednesday, April 8that 11:00 am.

 

 

Relevant publications from the speaker:

The nucleolus functions as a phase-separated protein quality control compartment.

Frottin F, Schueder F, Tiwary S, Gupta R, Körner R, Schlichthaerle T, Cox J, Jungmann R, Hartl FU, Hipp MS. Science. 2019 Jul 26;365(6451):342-347.

doi: 10.1126/science.aaw9157.

 

Advances in nuclear proteostasis of metazoans.

Buggiani J, Meinnel T, Giglione C, Frottin F. Biochimie. 2024 Nov;226:148-164.

doi: 10.1016/j.biochi.2024.04.006.

 

Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model.

Frottin F, Pérez-Berlanga M, Hartl FU, Hipp MS. Elife. 2021 Jun 23;10:e62718.

doi: 10.7554/eLife.62718.