Dr. Cristiano SIMONE

University of Bari Aldo Moro, Bari, Italy
Invited by Dr. Souhila MEDJKANE

“Unraveling SMYD3 functions along the Cancer Hallmark trail.” 

The seminar will take place in the Institut Jacques Monod seminar room (RB-18B).
Bâtiment Buffon, 15 rue Hélène Brion, Paris 13th.

On Wednesday, September 30th at 11:00 am.

Zoom link for remote attendees:
https://u-paris.zoom.us/j/86114422072?pwd=VzJ0c2pxcHl4OWppekx3MldlM2Y4QT09
Meeting ID: 861 1442 2072
Secret code:  492809

Relevant publications from the speaker

Tailoring a novel colorectal cancer stem cell-targeted therapy by inhibiting the SMYD3/c-MYC axis.
Lepore Signorile et al. 2025, doi: 10.1038/s41392-025-02290-z

The novel SMYD3 inhibitor EM127 impairs DNA repair response to chemotherapy-induced DNA damage and reverses cancer chemoresistance.
Sanese P et al. 2024, doi: 10.1186/s13046-024-03078-9

SMYD3 Modulates AMPK-mTOR Signaling Balance in Cancer Cell Response to DNA Damage.
Lepore Signorile et al. 2023, doi: 10.3390/cells12222644

Congratulations to Dr. Silvia Comunian!

Congratulations to Dr. Silvia Comunian!

On September 25, 2026, Silvia successfully defended her thesis: “Epigenetic control of nuclear mechanics and migration via H3K9 methylation at Lamina-Associated Domains in lung cancer cells”Silvia Comunian  and the jury members: Yegor Vassetzky, Nicolas Borghi,...

Welcome to Sara

Welcome to Sara

Sara is joining the team for a master’s internship. As a student in the Interdisciplinary Master’s in Life Sciences program at the Ecole Normale Superieure, Sara will contribute to a research project aimed at identifying vulnerabilities in DNA repair in high-grade...