Congratulations to Dr. Maeva Zamperoni!
On September 15, 2025, Maeva successfully defended her thesis: “Role of the lysine methyltransferase SETDB1 in TGFβ-induced fibrosis in Duchenne Muscular Dystrophy (DMD).”
Maeva and the jury members: Pascal Maire, Nicolas Reynoird, Sestina Falcone, Frédérique Magdinier, Véronique Joliot, Bert Blaauw, and Slimane Ait-Si-Ali
Congratulations to our dear Dr. Zamperoni! Brava!
Sagi Shapira seminar – March 1, 2023
Wednesday March 1st, 2023, at 11:00 am Sagi Shapira Systems Biology Laboratory, INEM, Université Paris CitéInvited by Jonathan Weitzman “Dissecting Viruses: From Cell Circuits to First Drafts” The seminar will take place in the Institut Jacques Monod seminar room...
Congratulations to Aris and Angélique !
The graduation of the 2021 and 2022 classes of the European Master of Genetics took place last Saturday during the G.E.N.E symposium 2023.Among the graduates, we are proud to count two members of the team: Aristeidis, PhD and Angélique, AI & Lab manager ! From...
Article : Species-specific regulation of XIST by the JPX/FTX orthologs
Congratulations to the team members for this new article about "Species-specific regulation of XIST by the JPX/FTX orthologs" published in Nucleic Acids Research (Feb 2023). Graphical abstract In contrast to the mouse, human JPX regulates XIST through mechanisms that...
Welcome to Gabrielle
Gabrielle is our new M2 student.She will work on immune-related host genes dowregulated by Theileria parasites. Welcome in the team Gabrielle ! Read more
Welcome Romina !
Romina Facchinello is joining the lab for her Master’s internship (Magistère Européen de Génétique). Welcome Romina!Read more
Brain organoids, new advances in research
"CNRS Le Journal" and "Le Monde" published a video article describing the new technical advances in the field of neurobiology, the preparation of human brain organoïds. They visited the Mezger laboratory to have a look at their experimental set up using cerebral...
Celebrating the 10 years of the Polo group
Jan 13th 2023: We had a wonderful time celebrating the 10-year anniversary of the lab, time flies! It was great to see past and current lab members together and to share warm memories. Great things can only be achieved when sourrounded by great people. Warm thanks to...
Daniele Fachinetti seminar – January 11, 2023
Wednesday January 11th, 2023, at 11:00 am Daniele Fachinetti Institut CurieInvited by Pierre-Antoine Defossez “Centromere instability: causes and consequences” The seminar will take place in the Institut Jacques Monod seminar room (RB-18B). Bâtiment Buffon, 15 rue...
Welcome to Eliane
January 3, 2023: Eliane Petit joined the group as a second year Master student to work on a proteomics project to map the chromatin landscape at sites of UV damage repair in human cells. Read more
Welcome to Sara
Sara is our new M2 student.She will work on the Methylation of ESCRT-III proteins by SMYD3 and its funtion in cell division. Welcome in the team Sara ! Read more
Congratulations to Aurélie De Thonel and the Mezger Lab for their paper in Nature Communications
Aurélie De Thonel and the V Mezger lab released a paper in Nature Communications elucidating the relationship between CBP and HSF2 in a neurodevelopmental disorder, CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder....
Claire Rougeulle receives the Janine Beisson 2022 medal
The French Society of Genetics (SFG) 2022 medal, Janine BEISSON prize, was awarded to Claire ROUGEULLE by her Professor of genetics Bernard DUJON (former president of the SFG) in the presence of the current vice-presidents of the SFG Clément Carré and Frédéric Bernard...
Team retreat on Tinos island
The team took advantage of a few days on Tinos island to present and discuss its results with the research teams of Edith Heard (EMBL) and Joost Gribnau (Erasmus MC). Nice moments of scientific exchanges between the...
Antoine Zalc seminar – November 23, 2022
Wednesday November 23th, 2022, at 11:00 am Antoine Zalc Cell fate plasticity and reprogramming, Institut Cochin, Université Paris CitéInvited by Jonathan Weitzman “Reactivation of cranial neural crest cells pluripotency programs: a crucial path in development and...
Elena Brivio seminar – November 17, 2022
Thursday November 17th, 2022, at 10:45 am Elena Brivio Weizmann Institute of Science, IsraelInvited by Valérie Mezger “Sex shapes cell-type-specific transcriptional signatures of stress exposure in the mouse hypothalamus” The seminar will take place in the Institut...
Jonathan Weitzman receives the Roy-Vaucouloux Prize
On October 18 and 22, the Académie des Sciences honoured 78 research actors for their talent and remarkable contributions to science. Jonathan Weitzman is one of them. © Académie des sciences The Academy of Sciences awards nearly 80 prizes each year, covering all...
Scientific symposium “Methylation signaling: Beyond histones and chromatin”
Protein methylation is emerging as a critical post-translational modification in signaling and cellular processes. New experimental approaches reveal that a large number of proteins are methylated and there is an emerging interest in the role of methylation of lysine...
Kathleen Stewart-Morgan seminar- September 28, 2022
Wednesday September 28th at 11:00 am Dr Kathleen Stewart-Morgan The Novo Nordisk Foundation Center for Protein Research, CopenhagenInvited by Sophie Polo and Nataliya Petryk “Quantifying propagation of DNA methylation and hydroxymethylation with EDIMS” The seminar...
Frédéric Berger seminar- September 21, 2022
Wednesday September 21st, 2022, at 11:00 am Frédéric Berger Austrian Academy of Sciences, ViennaInvited by Pierre-Antoine Defossez “When mothers take full control of embryo development: paternal chromosome repression in viviparous species” The seminar will take place...
Adrian Bird seminar – September 14, 2022
Wednesday September 14th, 2022, at 11:00 am Adrian Bird Wellcome Centre for Cell Biology, University of Edinburgh, UKInvited by Pierre-Antoine Defossez “Proteins that interpret genomic signals to stabilise cell identity” The seminar will take place in the Institut...