Elena Brivio seminar – November 17, 2022

Elena Brivio

Weizmann Institute of Science, Israel
Invited by Valérie Mezger

“Sex shapes cell-type-specific transcriptional signatures of stress exposure in the mouse hypothalamus”

The seminar will take place in the Institut Jacques Monod seminar room (RB-18B). Bâtiment Buffon, 15 rue Hélène Brion, Paris 13th.

Zoom link for remote attendees:
https://u-paris.zoom.us/j/86114422072?pwd=VzJ0c2pxcHl4OWppekx3MldlM2Y4QT09

Contact : sophie.polo@univ-paris-diderot.fr

Relevant publications from the speaker:
Ketamine exerts antidepressant effects via cell-type specific regulation of Kcnq2.
Lopez JP, Lücken MD, Brivio E, Karamihalev S, Kos A, De Donno C, Benjamin A, Yang H, Dick ALW, Stoffel R, Flachskamm C, Ressle A, Roeh S, Huettl RE, Parl A, Eggert C, Novak B, Yan Y, Yeoh K, Holzapfel M, Hauger B, Harbich D, Schmid B, Di Giaimo R, Turck CW, Schmidt MV, Deussing JM, Eder M, Dine J, Theis FJ, Chen A.
Neuron. 2022 Jul 20;110(14):2283-2298.e9. doi: 10.1016/j.neuron.2022.05.001.

Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation.
Lopez JP, Brivio E, Santambrogio A, De Donno C, Kos A, Peters M, Rost N, Czamara D, Brückl TM, Roeh S, Pöhlmann ML, Engelhardt C, Ressle A, Stoffel R, Tontsch A, Villamizar JM, Reincke M, Riester A, Sbiera S, Fassnacht M, Mayberg HS, Craighead WE, Dunlop BW, Nemeroff CB, Schmidt MV, Binder EB, Theis FJ, Beuschlein F, Andoniadou CL, Chen A.
Sci Adv. 2021 Jan 27;7(5):eabe4497. doi: 10.1126/sciadv.abe4497.

Sex differences: Transcriptional signatures of stress exposure in male and female brains.
Brivio E, Lopez JP, Chen A.
Genes Brain Behav. 2020 Mar;19(3):e12643. doi: 10.1111/gbb.12643.

Social dominance mediates behavioral adaptation to chronic stress in a sex-specific manner.
Karamihalev S*, Brivio E*, Flachskamm C, Stoffel R, Schmidt MV, Chen A.
Elife. 2020 Oct 9;9:e58723. doi: 10.7554/eLife.58723.