Dr. Fiona Francis

NeuroSU, Paris,France

Invited by Dr. Valérie Mezger

Progenitor cell mechanisms during cerebral cortical development

The seminar will take place in the Institut Jacques Monod seminar room (RB-18B).

Bâtiment Buffon, 15 rue Hélène Brion, Paris 13th.

On Wednesday,  February 18that 11:00 am.

Relevant publications from the speaker:

Unraveling LIS1-Lissencephaly: Insights from Cerebral Organoids Suggest Severity- Dependent Genotype-Phenotype Correlations, Molecular Mechanisms and Therapeutic Strategies.

Zillich L, Rossetti AC*, Fechtner O*, Gasparotto M, Maillard C, Hoffrichter A, Zillich E, Jabali A, Marsoner F, Wilkens R, Schroeter CB, Hentschel A, Meuth SG, Ruck T, Koch P, Roos A, Bahi-Buisson N, Francis F, Ladewig J Nat Commun. 16(1):9091. (2025)

Forebrain Eml1 depletion reveals early centrosomal dysfunction causing subcortical heterotopia

Zaidi D, Chinnappa K, Nur Yigit B, Viola V, Cifuentes-Diaz C, Jabali A, Uzquiano A, Lemesre E, Perez F, Ladewig J, Ferent J, Ozlu N, Francis F J Cell Biol Dec 2;223(12):e202310157. (2024)

Novel role of the synaptic scaffold protein Dlgap4 in ventricular surface integrity and neuronal migration during cortical development.

Romero DM, Poirier K, Belvindrah R, Moutkine I, Houllier A, LeMoing A-G, Petit F, Boland A, Collins SC, Soiza-Reilly M, Yalcin B, Chelly J, Deleuze J-F, Bahi-Buisson N, Francis F Nat Commun 13(1):2746 (2022)

Human cerebral organoids reveal progenitor pathology in EML1-linked cortical malformation.

Jabali A, Hoffrichter A, Uzquiano A, Marsoner F, Wilkens R, Siekmann M, Bohl B, Rossetti A, Horschitz S, Koch P, Francis F, Ladewig J EMBO Rep 23(5):e54027. (2022)

Welcome to Léa

Welcome to Léa

Léa joins the team as a research assistant. After completing a master's degree in virology, she worked in Strasbourg on grapevine viruses, then on characterizing mRNA degradation in plants at the Institute of Plant Molecular Biology (IBMP). In the Polo team, Léa will...

Welcome to Léa, new engineer in the team!

Welcome to Léa, new engineer in the team!

Léa joins the lab as a research assistant. She holds a Master's degree in Molecular and Cellular Biology from Sorbonne University. She will contribute to investigate DNA methylation maintenance mechanisms in response to UV damage in mammalian cells. Léa Girard À lire...

Well done, Dr Mori!

Well done, Dr Mori!

Margherita successfully defended her PhD on DNA methylation maintenance in response to UV damage. Brava! Margherita and her thesis jury. From left to right: Sophie Polo, Sandra Duharcourt (on screen), Déborah Bourc'his, Margherita Mori, Nataliya Petryk, Jean Molinier,...

Congratulations Dr Giacomini!

Congratulations Dr Giacomini!

Giulia defended her PhD on the impact of high grade glioma-associated histone H3 mutations on genome integrity. Congratulations to her on a fantastic thesis defense! Giulia Giacomini and her thesis jury. From left to right: Beatrice Rondinelli, Keith Caldecott,...