Dr. Jan Padeken
Institute of Molecular Biology, Mainz, Germany
“UV-Damage-induced Epigenetic Memory in Organismal Resilience and Aging.”
The seminar will take place in the Institut Jacques Monod seminar room (RB-18B).
Bâtiment Buffon, 15 rue Hélène Brion, Paris 13th.
On Wednesday, October 14th at 11:00 am.
Zoom link for remote attendees:
https://u-paris.zoom.us/j/86114422072?pwd=VzJ0c2pxcHl4OWppekx3MldlM2Y4QT09
Meeting ID: 861 1442 2072
Secret code: 492809
Relevant publications from the speaker
Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance.
Padeken J, Methot SP, Gasser SM. Nat Rev Mol Cell Biol. 2022 Sep;23(9):623-640. doi: 10.1038/s41580-022-00483-w.
SETDB1-like MET-2 promotes transcriptional silencing and development independently of its H3K9me-associated catalytic activity.
Delaney CE, Methot SP, Kalck V, Seebacher J, Hess D, Gasser SM, Padeken J. Nat Struct Mol Biol. 2022 Feb;29(2):85-96. doi: 10.1038/s41594-021-00712-4.
H3K9me selectively blocks transcription factor activity and ensures differentiated tissue integrity.
Methot SP*, Padeken J*, Brancati G, Zeller P, Delaney CE, Gaidatzis D, Kohler H, van Oudenaarden A, Großhans H, Gasser SM. Nat Cell Biol. 2021 Nov;23(11):1163-1175. doi: 10.1038/s41556-021-00776-w.
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