Dr. Benoît MOINDROT
The Institute for Integrative Biology of the Cell (I2BC), University Paris-Saclay
Invited by Dr. Dounia DJEGHLOUL
“One Genome, Two Voices: Decoding allelic chromatin-regulatory layers, and their perturbations, at imprinted domains.”
The seminar will take place in the Institut Jacques Monod seminar room (RB-18B).
Bâtiment Buffon, 15 rue Hélène Brion, Paris 13th.
On Wednesday, July 8th at 11:00 am.
Zoom link for remote attendees:
https://u-paris.zoom.us/j/86114422072?pwd=VzJ0c2pxcHl4OWppekx3MldlM2Y4QT09
Meeting ID: 861 1442 2072
Secret code: 492809
Relevant publications from the speaker:
-
Imaizumi, Y. et al. DNA methylation and lncRNA control asynchronous DNA replication at specific imprinted gene domains. Nat Commun. (2026)
DOI: 10.1038/s41467-026-68558-2 -
Farhadova, S. et al. The long non-coding RNA Meg3 mediates imprinted gene expression during stem cell differentiation. Nucleic Acids Res. (2024)
DOI: 10.1093/nar/gkae247 -
Llères, D. et al. CTCF modulates allele-specific sub-TAD organization and imprinted gene activity at the mouse Dlk1-Dio3 and Igf2-H19 domains. Genome Biol. (2019)
DOI: 10.1186/s13059-019-1896-8
Minoru Yoshida Seminar – February 20, 2026
Pr. Minoru Yoshida Executive Vice-President of RIKEN, Leader of the Chemical Genomics Research GroupRIKEN Center for Sustainable Resource Science, Wako, Japan Invited by Dr. Pierre-Antoine Defossez "Tackling Genetic Diseases with Chemical Biology" The seminar will...
Fiona Francis Seminar – February 18, 2026
Dr. Fiona Francis NeuroSU, Paris,France Invited by Dr. Valérie Mezger "Progenitor cell mechanisms during cerebral cortical development" The seminar will take place in the Institut Jacques Monod seminar room (RB-18B). Bâtiment Buffon, 15 rue Hélène Brion, Paris 13th....
Pauline Spéder Seminar – February 4, 2026
Dr. Pauline Spéder Institut Pasteur, Paris, France Invited by Dr. Valérie Mezger "Under pressure: forces and resistance in the neurogenic niche" The seminar will take place in the Institut Jacques Monod seminar room (RB-18B). Bâtiment Buffon, 15 rue Hélène Brion,...
Laure Bally-Cuif Seminar – January 28, 2026
Dr. Laure Bally-Cuif Institut Pasteur and CNRS, Paris, France Invited by Dr. Valérie Mezger "Making sense of adult Neural Stem Cell heterogeneities" The seminar will take place in the Institut Jacques Monod seminar room (RB-18B). Bâtiment Buffon, 15 rue Hélène Brion,...
Welcome to Léa
Léa joins the team as a research assistant. After completing a master's degree in virology, she worked in Strasbourg on grapevine viruses, then on characterizing mRNA degradation in plants at the Institute of Plant Molecular Biology (IBMP). In the Polo team, Léa will...
Sophie Polo receives an Impulscience® grant from the Fondation Bettencourt Schueller
Sophie Polo has been awarded an Impulscience® grant to fund a research project on the establishment and maintenance of the inactive X chromosome in response to DNA breaks. This is wonderful news for the lab ! We thank the Fondation Bettencourt Schueller for their...
Welcome to Léa, new engineer in the team!
Léa joins the lab as a research assistant. She holds a Master's degree in Molecular and Cellular Biology from Sorbonne University. She will contribute to investigate DNA methylation maintenance mechanisms in response to UV damage in mammalian cells. Léa Girard À lire...
Well done, Dr Mori!
Margherita successfully defended her PhD on DNA methylation maintenance in response to UV damage. Brava! Margherita and her thesis jury. From left to right: Sophie Polo, Sandra Duharcourt (on screen), Déborah Bourc'his, Margherita Mori, Nataliya Petryk, Jean Molinier,...
Congratulations Dr Giacomini!
Giulia defended her PhD on the impact of high grade glioma-associated histone H3 mutations on genome integrity. Congratulations to her on a fantastic thesis defense! Giulia Giacomini and her thesis jury. From left to right: Beatrice Rondinelli, Keith Caldecott,...
Congratulations to Dr. Maeva Zamperoni!
On September 15, 2025, Maeva successfully defended her thesis: “Role of the lysine methyltransferase SETDB1 in TGFβ-induced fibrosis in Duchenne Muscular Dystrophy (DMD).”Maeva and the jury members: Pascal Maire, Nicolas Reynoird, Sestina Falcone, Frédérique...
Congratulations to Jérémy, newly appointed Associate Professor!
We are delighted to announce Jérémy Berthelet's success in the Assistant Professor competition!On September 1, 2025, Jérémy officially joined our laboratory as a civil servant lecturer-researcher (trainee). This position is an important step, not only in his career,...
Congratulations to Souhila, promoted full Professor !
We are delighted to announce the success of Souhila MEDJKANE, who has been promoted to full Professor!On September 1, 2025, Souhila was officially promoted to Professor. This is a major milestone in her career, and a source of great pride for our team and the teaching...
Congratulations to Delphine and Julia for their research funding
Congratulations to Delphine Burlet on getting a postdoctoral grant from the Fondation de France and to Julia Roche Dupuy who obtained a fellowship from the HOB doctoral school to finance her PhD thesis. Delphine Burlet, Julia Roche Dupuy À lire aussi
Welcome to Annabelle, new post-doc in the team!
Annabelle joins the lab as a post-doctoral fellow. She completed her PhD at the University of Oxford under the supervision of Prof. Monika Gullerova. Her doctoral work focused on the role of small non-coding Y RNAs and the RNA-binding protein, YBX1, in intracellular...
Welcome to Orlane
Today, we welcome a new member to the team: Orlane. She's a student from the first year of the Brevet de Technicien Supérieur Biotechnologies en Recherche et Production (Two-year technical degree - Biotechnologies in Research and Production).Orlane will be working...
4th year PhD fellowships for Anaëlle
Congratulations to Anaëlle Azogui for obtaining a 4th year PhD fellowships from the "Fondation pour la recherche sur le cancer" (Fondation ARC). Read more
Congratulations to the Defossez team for their article published in Nature Communication
Congratulations to the Defossez team for their article “DNA methylation protects cancer cells against senescence” by Chen, Yamaguchi, et al., which has been accepted in Nature Communication. Read it here: doi:doi: https://doi.org/10.1101/2024.08.23.609297...
Welcome to Delphine, new post-doc in the team!
Delphine joins the lab as a post-doctoral fellow. She completed her PhD at the Centre de Recherche en Cancérologie de Lyon (CRCL) under the supervision of Virginie Petrilli. Her doctoral work focused on the pro-inflammatory protein NLRP3, for which she highlighted a...
New research article on how chromatin marking governs DNA damage segregation in mitosis
In this paper, we uncover a damaged chromatin marking mechanism that drives the non-random segregation of UV damage through mitosis with potential consequences on daughter cell fate. Thus, we reveal that chromatin alterations impinge on genome stability not only by...
Welcome to Julia
Julia Roche Dupuy joined the lab for her second year Master's internship. Julia Roche Dupuy Second year Master's student À lire aussi