Romina Facchinello is joining the lab for her Master’s internship (Magistère Européen de Génétique).
Welcome Romina!
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New review: X chromosome regulation and female functional specificities: Are two Xs better than one?
What if the presence of two X chromosomes confers functional specificities on female cells and contributes to the different susceptibilites of men and women to certain diseases? One of the X chromosomes is randomly silenced in each female cell from the embryonic...
New review: Unleashing XIST from X-chromosome inactivation
The discovery that long noncoding RNAs (lncRNAs) are the most abundant gene class in the human genome has sparked significant research, particularly on Xist, a key RNA involved in X-chromosome inactivation. Recent studies have expanded our understanding of Xist's...
Congratulations Dr Carrillo
Congratulations to Léo who defended his thesis work on " Exploring the link between X chromosome inactivation and the development of human extraembryonic tissues " . © Rougeulle team À lire aussi
Article: XIST dampens X chromosome activity in a SPEN-dependent manner during early human development
Our latest work carried out by Alfeghaly C. et al. elucidating the mechanism of dampening of X-linked gene expression during pre-implantation development. To discover the role of the long non-coding RNA XIST and its particular partner SPEN click on the link: Nature...