Jan 16, 2025 | Polo group
In this paper, we uncover a damaged chromatin marking mechanism that drives the non-random segregation of UV damage through mitosis with potential consequences on daughter cell fate. Thus, we reveal that chromatin alterations impinge on genome stability not only by...
Jan 13, 2025 | Polo group
Julia Roche Dupuy joined the lab for her second year Master’s internship. Julia Roche Dupuy Second year Master’s student À lire aussi New research article on how chromatin marking governs DNA damage segregation in mitosis Polo groupIn this paper, we...
Jun 11, 2024 | Polo group, Publications
A review from our research group is out for publication in DNA Repair as part of the special issue “Cutting-Edge Perspectives in Genome Maintenance”. This review presents our current knowledge on the contribution of pre-existing and DNA damage-induced...
May 30, 2024 | Polo group
Congratulations to Giulia Giacomini and Margherita Mori for obtaining 4th year PhD fellowships from the Fondation pour la Recherche Médicale (FRM) and la Ligue contre le Cancer. Giulia Giacomini (left) and Margherita Mori (right) © Eliane Petit À lire aussi 4th year...
Jan 27, 2024 | Polo group, Symposia and seminars
Sophie Polo is co-organizing the third edition of the EMBO Workshop “Chromatin dynamics and nuclear organization in genome maintenance”. © https://meetings.embo.org/event/24-chromatin-dynamics The workshop will take place in Leiden, Netherlands, from June...
Jan 12, 2024 | Polo group, Publications
January 12th 2024: We have uncovered an altered DNA repair activity in H3.3 mutant pediatric high-grade glioma that fosters genome instability independently of previously described oncogenic pathways. Furthermore, we have identified a DNA repair enzyme that sustains...
Mar 17, 2023 | Polo group
March 17th 2023: Sophie Polo and Beatrice Rondinelli received 80,000 € funding support from the French Society for Pediatric Cancers (SFCE), joint contribution from Imagine for Margo and Enfants Cancer Santé. This will help validating a new therapeutic target in...
Jan 13, 2023 | Polo group
Jan 13th 2023: We had a wonderful time celebrating the 10-year anniversary of the lab, time flies! It was great to see past and current lab members together and to share warm memories. Great things can only be achieved when sourrounded by great people. Warm thanks to...
