EpiG : Functional epigenomics
The Functional Epigenomics platform’s objectives are to provide equipment and to train staff in its use.
It offers services for epigenome analysis and participates in the development of new techniques according to the evolution of the field.
The Functional Epigenomics platform is open to the academic and industrial scientific community.
Scheme of platform’s expertise
Epigenomic Platform offers support in the design, production and interpretation of epigenomic experiments.
© Laure Ferry
Expertise
The epigenomic platform offers expertise in analysis of epigenetic marks. It evaluates the feasibility of submitted projects and proposes the most suitable method for their completion.
DNA Methylation
- LUMA (LUminometric Methylation Assay)
- MeDIP ou hMeDIP (Methylated or hydroxyMethylated Immunoprecipitation Assay)
- Bisulfite pyrosequencing
Histones Marks
- Cut & Run
- ChIP
Submit a project
You can contact us for any questions or to discuss your project together.
You must fill in the project request form and send it to the following address: parisepigenetics.pf@gmail.com
Developments
The Functional Epigenomic platform is involved in the development of new techniques for epigenome analysis:
- Cut & Run automatisation
- Cut & Tag
- Enzymatic Methyl-seq ( EM-seq)
- Nanopore
Epigenetic analyses available
Services for DNA methylation and histone marks analyses
Equipment
Equipment available on the Epigenomic platform
Members
Publications
- Planques A, Pierre K, Ferry L, Grunau C, Gazave E, Vervoort M. DNA methylation atlas and machinery in the developing and regenerating annelid Platynereis dumerilii. BMC Biology, Vol 19, Iss 1, Pp 1-26, 2021. DOI: 10.1186/s12915-021-01074-5
- Marchal C, de Dieuleveult M, Saint-Ruf C, Guinot N, Ferry L, Olalla Saad ST, Lazarini M, Defossez PA, Miotto B. Depletion of ZBTB38 potentiates the effects of DNA demethylating agents in cancer cells via CDKN1C mRNA up-regulation. Oncogenesis; Oct 2018, Vol. 7 Issue 10, p1-18, 18p DOI: 10.1038/s41389-018-0092-0
- Velasco G, Grillo G, Touleimat N, Ferry L, Ivkovic I, Ribierre F, Deleuze JF, Chantalat S, Picard C, Francastel C. Comparative methylome analysis of ICF patients identifies heterochromatin loci that require ZBTB24, CDCA7 and HELLS for their methylated state. Human Molecular Genetics, 2018 Jul 15;27(14):2409-2424. DOI: 10.1093/hmg/ddy130.
- Ferry L, Fournier A, Tsusaka T, Adelmant G, Shimazu T, Matano S, Kirsh O, Amouroux R, Dohmae N, Suzuki T, Filion GJ, Deng W, de Dieuleveult M, Fritsch L, Kudithipudi S, Jeltsch A, Leonhardt H, Hajkova P, Marto JA, Arita K, Shinkai Y, Defossez PA. Methylation of DNA Ligase 1 by G9a/GLP Recruits UHRF1 to Replicating DNA and Regulates DNA Methylation. Molecular Cell. August 17, 2017, Vol. 67 Issue 4, p550. DOI: 10.1016/j.molcel.2017.07.012
- Kebir O, Chaumette B, Rivollier F, Miozzo F, Lemieux Perreault LP, Barhdadi A, Provost S, Plaze M, Bourgin J, the ICAAR team, Gaillard R, Mezger V, Dubé M-P , Krebs M-O. Methylomic changes during conversion to psychosis. Molecular Psychiatry (2017) 22, 512-518. DOI: 10.1038/mp.2016.53.
Contact
You can contact us at: parisepigenetics.pf@gmail.com
Functional Epigenomic Platform
35 rue Hélène Brion
Bâtiment Lamarck B, RB77-81
75013 PARIS
+33(0)1 57 27 89 26
Read more
Welcome to Léa, new engineer in the team!
Léa joins the lab as a research assistant. She holds a Master's degree in Molecular and Cellular Biology from Sorbonne University. She will contribute to investigate DNA methylation maintenance mechanisms in response to UV damage in mammalian cells. Léa Girard À lire...
Well done, Dr Mori!
Margherita successfully defended her PhD on DNA methylation maintenance in response to UV damage. Brava! Margherita and her thesis jury. From left to right: Sophie Polo, Sandra Duharcourt (on screen), Déborah Bourc'his, Margherita Mori, Nataliya Petryk, Jean Molinier,...
Congratulations Dr Giacomini!
Giulia defended her PhD on the impact of high grade glioma-associated histone H3 mutations on genome integrity. Congratulations to her on a fantastic thesis defense! Giulia Giacomini and her thesis jury. From left to right: Beatrice Rondinelli, Keith Caldecott,...
Congratulations to Dr. Maeva Zamperoni!
On September 15, 2025, Maeva successfully defended her thesis: “Role of the lysine methyltransferase SETDB1 in TGFβ-induced fibrosis in Duchenne Muscular Dystrophy (DMD).”Maeva and the jury members: Pascal Maire, Nicolas Reynoird, Sestina Falcone, Frédérique...