Wednesday, June 7th, 2023, at 11:00 am
Agathe Subtil
CNRS UMR3691, Institut Pasteur, Paris
Invited by Slimane Ait-Si-Ali and Sophie Polo
“Imprint of Chlamydia infection on the metabolism and epigenome of epithelial host cells”
The seminar will take place in the Institut Jacques Monod seminar room (RB-18B). Buffon building, 15 rue Hélène Brion, Paris 13th.
Zoom link for remote attendees:
https://u-paris.zoom.us/j/86114422072?pwd=VzJ0c2pxcHl4OWppekx3MldlM2Y4QT09
Contact: sophie.polo@univ-paris-diderot.fr
Relevant publications from the speaker:
Sequestration of host metabolism by an intracellular pathogen.
Gehre L, Gorgette O, Perrinet S, Prevost MC, Ducatez M, Giebel AM, Nelson DE, Ball SG, Subtil A.Elife. 2016 Mar 16;5:e12552. doi: 10.7554/eLife.12552.
Infection-driven activation of transglutaminase 2 boosts glucose uptake and hexosamine biosynthesis in epithelial cells.
Maffei B, Laverrière M, Wu Y, Triboulet S, Perrinet S, Duchateau M, Matondo M, Hollis RL, Gourley C, Rupp J, Keillor JW, Subtil A. EMBO J. 2020 Apr 15;39(8):e102166. doi: 10.15252/embj.2019102166. Epub 2020 Mar 5.
Chlamydia trachomatis development requires both host glycolysis and oxidative phosphorylation but has only minor effects on these pathways.
N’Gadjaga MD, Perrinet S, Connor MG, Bertolin G, Millot GA, Subtil A. J Biol Chem. 2022 Sep;298(9):102338. doi: 10.1016/j.jbc.2022.102338. Epub 2022 Aug 2.
Read more
Seminar Adam SATERIALE –June 17, 2026
Dr. Adam Sateriale The Francis Crick Institute, London, UK Invited by Jonathan Weitzman and Marisol Giacomini "Intestinal parasites and metabolic mysteries." The seminar will take place in the Institut Jacques Monod seminar room (RB-18B). Bâtiment Buffon, 15...
Seminar Laurent CHATRE –June 10, 2026
Dr. Laurent CHATRE STCT, UMR6030 CNRS, Université de Caen Normandie, France Invited by Dr. Dounia DJEGHLOUL "Reframing Epigenetics: Metabolism, Mitochondria, and Redox as Core Regulatory Layers" The seminar will take place in the Institut Jacques Monod seminar...
Seminar Michael Rera –June 3, 2026
Dr. Michael Rera Department of Functional and Adaptive Biology, Université Paris Cité, France Invited by Dr. Valerie Mezger "Studying ageing as a two-phase process." The hallmarks of aging framework, introduced over a decade ago and cited nearly 20,000 times, became...
Seminar Anne-Sophie Lebre– May 27, 2026
Pr. Anne-Sophie Lebre CHU de Reims - Hôpital Robert Debré, France Invited by Pr. Bertrand Cosson "Brain (epi)genome study in CNS rare disorders" The seminar will take place in the Institut Jacques Monod seminar room (RB-18B). Bâtiment Buffon, 15 rue Hélène Brion,...