New collaborative paper accepted in Scientific Reports for the Defossez group

Congratulations to Laure and Pierre-Antoine for their collaborative paper accepted in Scientific Reports:

“Unchanged PCNA and DNMT1 dynamics during replication in DNA ligase I-deficient cells but abnormal chromatin levels of non-replicative histone H1”

Bhandari SK, Wiest N, Sallmyr A, Du R, Ferry L, Defossez PA, and Tomkinson AE
Sci Rep 13, 4363 (2023). https://doi.org/10.1038/s41598-023-31367-4

New research article on how chromatin marking governs DNA damage segregation in mitosis

Polo group

In this paper, we uncover a damaged chromatin marking mechanism that drives the non-random segregation of UV damage through mitosis with potential consequences on daughter cell fate. Thus, we reveal that chromatin alterations impinge on genome stability not only by...

Welcome to Julia

Polo group

Julia Roche Dupuy joined the lab for her second year Master's internship. Julia Roche Dupuy Second year Master's student À lire aussi

Welcome Caroline to our team!

Ait-Si-Ali group

We're excited to have Caroline joining Dr. Ait-si-Ali's team! She comes to us as an M2 student from the GENE2 master's program at Université Paris-Saclay. Working with Dr. Guillaume Velasco, Caroline will study the regulation of nuclear stiffness by H3K9...

Welcome Minh to Slimane Ait-si-ali’s team!