Wednesday, March 6, 2024, at 11:00 am
Manuel Muñoz
University of Buenos Aires-CONICET, Argentina
Invited by Sophie Polo
“RNA polymerase II abundance is controlled by DNA repair”
The seminar will take place in the Institut Jacques Monod seminar room (RB-18B). Buffon building, 15 rue Hélène Brion, Paris 13th.
Zoom link for remote attendees:
https://u-paris.zoom.us/j/86114422072?pwd=VzJ0c2pxcHl4OWppekx3MldlM2Y4QT09
Contact: sophie.polo@univ-paris-diderot.fr
Relevant publications from the speaker:
DNA Damage-Induced RNAPII Degradation and Its Consequences in Gene Expression.
Muñoz JC, Beckerman I, Choudhary R, Bouvier LA, Muñoz MJ. Genes (Basel). 2022 Oct 26;13(11):1951. doi: 10.3390/genes13111951.
GSK-3 is an RNA polymerase II phospho-CTD kinase.
Nieto Moreno N, Villafañez F, Giono LE, Cuenca C, Soria G, Muñoz MJ, Kornblihtt AR. Nucleic Acids Res. 2020 Jun 19;48(11):6068-6080. doi: 10.1093/nar/gkaa322.
Coupling between nucleotide excision repair and gene expression.
Cambindo Botto AE, Muñoz JC, Muñoz MJ. RNA Biol. 2018;15(7):845-848. doi: 10.1080/15476286.2018.1464354. Epub 2018 May 17.
Major Roles for Pyrimidine Dimers, Nucleotide Excision Repair, and ATR in the Alternative Splicing Response to UV Irradiation.
Muñoz MJ, Nieto Moreno N, Giono LE, Cambindo Botto AE, Dujardin G, Bastianello G, Lavore S, Torres-Méndez A, Menck CFM, Blencowe BJ, Irimia M, Foiani M, Kornblihtt AR. Cell Rep. 2017 Mar 21;18(12):2868-2879. doi: 10.1016/j.celrep.2017.02.066.
Read more
![Welcome Caroline to our team!](https://epigenetics.u-paris.fr/wp-content/uploads/sites/32/2025/01/Caroline-1920-1080-1080x675.jpg)
Welcome Caroline to our team!
We're excited to have Caroline joining Dr. Ait-si-Ali's team! She comes to us as an M2 student from the GENE2 master's program at Université Paris-Saclay. Working with Dr. Guillaume Velasco, Caroline will study the regulation of nuclear stiffness by H3K9...
![Welcome Minh to Slimane Ait-si-ali’s team!](https://epigenetics.u-paris.fr/wp-content/uploads/sites/32/2025/01/Minh-1920_1080-1080x675.jpg)
Welcome Minh to Slimane Ait-si-ali’s team!
We are delighted to welcome Mynh, an M2 student from the GENE2 master's program at Université Paris-Saclay, to Dr. Ait-si-Ali's team. Mynh will be investigating the role of SETDB1 in Duchenne muscular dystrophy phenotype development.
![Welcome to Steve](https://epigenetics.u-paris.fr/wp-content/uploads/sites/32/2025/01/Steve_JW-1080x675.jpg)
Welcome to Steve
Today, we welcome a new member to the team: Steve, a M2 student from the Magistère Européen de Génétique and an EUR GENE fellow.Steve will be working on the interactions of recently identified new parasite protein.Read more
![New review: X chromosome regulation and female functional specificities: Are two Xs better than one?](https://epigenetics.u-paris.fr/wp-content/uploads/sites/32/2024/12/CR-revue-C.Morey-2024-1080x675.jpg)
New review: X chromosome regulation and female functional specificities: Are two Xs better than one?
What if the presence of two X chromosomes confers functional specificities on female cells and contributes to the different susceptibilites of men and women to certain diseases? One of the X chromosomes is randomly silenced in each female cell from the embryonic...