Wednesday September 14th, 2022, at 11:00 am

Adrian Bird

Wellcome Centre for Cell Biology, University of Edinburgh, UK
Invited by Pierre-Antoine Defossez

“Proteins that interpret genomic signals to stabilise cell identity”

The seminar will take place in the Institut Jacques Monod seminar room (RB-18B). Bâtiment Buffon, 15 rue Hélène Brion, Paris 13th.

Zoom link for remote attendees:
https://u-paris.zoom.us/j/86114422072?pwd=VzJ0c2pxcHl4OWppekx3MldlM2Y4QT09

Contact: sophie.polo@univ-paris-diderot.fr

 

Relevant publications from the speaker:

Neuronal non-CG methylation is an essential target for MeCP2 function.
Tillotson R, Cholewa-Waclaw J, Chhatbar K, Connelly JC, Kirschner SA, Webb S, Koerner MV, Selfridge J, Kelly DA, De Sousa D, Brown K, Lyst MJ, Kriaucionis S, Bird A.
Mol Cell. 2021 Mar 18;81(6):1260-1275.e12. doi: 10.1016/j.molcel.2021.01.011.

SALL4 controls cell fate in response to DNA base composition.
Pantier R, Chhatbar K, Quante T, Skourti-Stathaki K, Cholewa-Waclaw J, Alston G, Alexander-Howden B, Lee HY, Cook AG, Spruijt CG, Vermeulen M, Selfridge J, Bird A.
Mol Cell. 2021 Feb 18;81(4):845-858.e8. doi: 10.1016/j.molcel.2020.11.046.

Quantitative modelling predicts the impact of DNA methylation on RNA polymerase II traffic.
Cholewa-Waclaw J, Shah R, Webb S, Chhatbar K, Ramsahoye B, Pusch O, Yu M, Greulich P, Waclaw B, Bird AP.
Proc Natl Acad Sci U S A. 2019 Jul 23;116(30):14995-15000. doi: 10.1073/pnas.1903549116.

 

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