Séminaire Adrian Bird- 14 septembre 2022

Adrian Bird

Wellcome Centre for Cell Biology, University of Edinburgh, UK
Invité par Pierre-Antoine Defossez

“Proteins that interpret genomic signals to stabilise cell identity”

Le séminaire se tiendra à l’Institut Jacques Monod, salle François Jacob (RB-18B). Bâtiment Buffon, 15 rue Hélène Brion, Paris 13.

Lien Zoom pour les participants en distanciel :
https://u-paris.zoom.us/j/86114422072?pwd=VzJ0c2pxcHl4OWppekx3MldlM2Y4QT09

Contact : sophie.polo@univ-paris-diderot.fr

Publications de l’intervenant :

Neuronal non-CG methylation is an essential target for MeCP2 function.
Tillotson R, Cholewa-Waclaw J, Chhatbar K, Connelly JC, Kirschner SA, Webb S, Koerner MV, Selfridge J, Kelly DA, De Sousa D, Brown K, Lyst MJ, Kriaucionis S, Bird A.
Mol Cell. 2021 Mar 18;81(6):1260-1275.e12. doi: 10.1016/j.molcel.2021.01.011.

SALL4 controls cell fate in response to DNA base composition.
Pantier R, Chhatbar K, Quante T, Skourti-Stathaki K, Cholewa-Waclaw J, Alston G, Alexander-Howden B, Lee HY, Cook AG, Spruijt CG, Vermeulen M, Selfridge J, Bird A.
Mol Cell. 2021 Feb 18;81(4):845-858.e8. doi: 10.1016/j.molcel.2020.11.046.

Quantitative modelling predicts the impact of DNA methylation on RNA polymerase II traffic.
Cholewa-Waclaw J, Shah R, Webb S, Chhatbar K, Ramsahoye B, Pusch O, Yu M, Greulich P, Waclaw B, Bird AP.
Proc Natl Acad Sci U S A. 2019 Jul 23;116(30):14995-15000. doi: 10.1073/pnas.1903549116.