Séminaire Agathe Subtil – 7 juin 2023

Agathe Subtil

CNRS UMR3691, Institut Pasteur, Paris
Invitée par Slimane Ait-Si-Ali et Sophie Polo

“Imprint of Chlamydia infection on the metabolism and epigenome of epithelial host cells”

Le séminaire se tiendra à l’Institut Jacques Monod, salle François Jacob (RB-18B). Bâtiment Buffon, 15 rue Hélène Brion, Paris 13.

Lien Zoom pour les participants en distanciel :
https://u-paris.zoom.us/j/86114422072?pwd=VzJ0c2pxcHl4OWppekx3MldlM2Y4QT09

Contact : sophie.polo@univ-paris-diderot.fr

Publications de l’intervenante :

Sequestration of host metabolism by an intracellular pathogen.
Gehre L, Gorgette O, Perrinet S, Prevost MC, Ducatez M, Giebel AM, Nelson DE, Ball SG, Subtil A.Elife. 2016 Mar 16;5:e12552. doi: 10.7554/eLife.12552.

Infection-driven activation of transglutaminase 2 boosts glucose uptake and hexosamine biosynthesis in epithelial cells.
Maffei B, Laverrière M, Wu Y, Triboulet S, Perrinet S, Duchateau M, Matondo M, Hollis RL, Gourley C, Rupp J, Keillor JW, Subtil A. EMBO J. 2020 Apr 15;39(8):e102166. doi: 10.15252/embj.2019102166. Epub 2020 Mar 5.

Chlamydia trachomatis development requires both host glycolysis and oxidative phosphorylation but has only minor effects on these pathways.
N’Gadjaga MD, Perrinet S, Connor MG, Bertolin G, Millot GA, Subtil A. J Biol Chem. 2022 Sep;298(9):102338. doi: 10.1016/j.jbc.2022.102338. Epub 2022 Aug 2.